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How do we make blood clots? Google Classroom About Transcript Uncover the body's strategy for blood clotting to halt excessive blood loss. Learn about the crucial roles of endothelial cells, platelets, and fibrin in creating a platelet plug.


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Clotting Factors. Several activated clotting factors are serine proteases, including Factors 10 (X), 11 (XI), and 12 (XII), Thrombin. and Plasmin.. But the serpin has another trick to play. The protease makes a cut in the serpin leading to the formation of a covalent bond linking the two molecules, a massive allosteric change in the tertiary.


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Clotting factors are substances in the blood that act in sequence to stop bleeding by forming a clot. Here's a mnemonic to help you remember them ^___^ Clotting factors mnemonic I Fibrinogen II Prothrombin III Tissue factor IV Calcium V Proaccelerin, Labile factor VI Unassigned - Old name of Factor Va VII Stable factor, proconvertin


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Without active vitamin K, the vitamin K dependent factors will not mature. If the coagulation cascade has missing factors, then coagulation or blood clotting cannot occur. As a result, warfarin serves as an anticoagulant. Memory Trick. The trick to remember the vitamin K dependent components of the coagulation cascade is to use the following.


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1. Memorize the mnemonic FACS 10 PRO. 2. Associate each letter with a clotting factor. 3. Use the mnemonic to remember the clotting factors in order. 4. Remember that Factor VI is not a real clotting factor. It was thought to exist in the past but has since been disproven. Understanding the Clotting Factors


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Coagulation of blood occurs through a series of reactions due to the activation of a group of substances called clotting factors. There are 13 clotting factors identified and named after the scientists who discovered them or as per the activity. Only factor IX or Christmas factor is named after the patient in whom it was discovered.


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The clotting factors are Factor I (fibrinogen), Factor II (prothrombin), Factor III (tissue thromboplastin or tissue factor), Factor IV (ionized calcium), Factor V (labile factor.


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Memorize Blood clotting factors and their functions - This lecture explains the easy way to remember the blood clotting factors and their functions with the help of simple mnemonics and tricks..


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When you cut or another injury that causes bleeding, your clotting factors work together to form a blood clot. The clot prevents you from losing too much blood. This process is called the coagulation cascade. Also Known as: Coagulation Fators, Factor Assays, Blood Clotting Factors, Clotting Factors, Factor I, Factor II, Factor III, Factor IV.


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Clotting factor IV is a calcium ion that plays an important role in all 3 pathways. Some of the clotting factors function as serine proteases, specifically factors II, VI, IX, and X. Go to: Cellular Level The overwhelming majority of clotting factors are manufactured principally in hepatocytes.


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One important clotting factor is fibrin, a long, thin, and sticky protein. When it is turned on, it forms a mesh to hold the platelet plug in place. This is called a fibrin clot. The mesh also traps red blood cells to form a blood clot. The platelets contract to pull the two sides of the damaged vessel closer together, so it is easier to repair


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Clotting factor may be defined as " the substance or group of substances that help in clot formation (coagulation) is called clotting factor. Clot formation/ coagulation is not a one step process. There are two different pathways i.e intrinsic and extrinsic pathways of coagulation.


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Activity of proteins found in blood that work with platelets to help the blood clot (clotting factors) Blood Clots: Plugging the Breaks When an injury causes a blood vessel wall to break, platelets are activated. They change shape from round to spiny, stick to the broken vessel wall and each other, and begin to plug the break.


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1. Aim of coagulation cascade is to lay down fibrin, hence the final step involves: Factor I: Fibrinogen which is converted to Fibrin Factor XIII: Fibrin stabilizing factor which cross-links the Fibrin 2. Coagulation cascade is activated by 2 pathways, the extrinsic and intrinsic which culminates into a common pathway.


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clotting factor/trick/mnemonicsStep by step explanationeasy explanationIf u find this video informativeLIKE SHARE AND SUBSCRIBEAnd stay tuned to BEHCHAN DENT.